1,782 research outputs found
Emulating opportunistic networks with KauNet Triggers
In opportunistic networks the availability of an end-to-end path is no longer required. Instead opportunistic networks may take advantage of temporary connectivity opportunities.
Opportunistic networks present a demanding environment for network emulation as the traditional emulation setup, where application/transport endpoints only send and receive packets from the network following a black box approach,
is no longer applicable. Opportunistic networking protocols
and applications additionally need to react to the dynamics of the underlying network beyond what is conveyed through the exchange of packets.
In order to support IP-level emulation evaluations of applications and protocols that react to lower layer events, we have proposed the use of emulation triggers. Emulation triggers can emulate arbitrary cross-layer feedback and can be synchronized with other emulation effects. After introducing the design and implementation of
triggers in the KauNet emulator, we describe the integration of triggers with the DTN2 reference implementation and illustrate how the functionality can be used to emulate a classical DTN data-mule scenario
The Sky Arrow ERA, an innovative airborne platform to monitor mass, momentum and energy exchange of ecosystems
Substantial worldwide efforts are underway aimed at identifying the spatial and temporal distribution of the
global sources and sinks of atmospheric carbon dioxide (CO2). The sink/source strength of vegetated surfaces at
ground sites can now be estimated with reasonable accuracy and micrometeorological techniques are now well
established, while difficulties exist in up scaling these figures to the regional and global scales. Airborne measurement
of mass, momentum, and energy fluxes for boundary layer research has been available for decades requiring
the use of large aircraft to carry instruments and dedicated support facilities. The advent of compact, lowpower
instruments and high speed, high-capacity digital data acquisition systems has recently allowed small research
aircraft to perform such measurements with high accuracy. This paper first describes the Sky Arrow ERA
(Environmental Research Aircraft), a small research aircraft that has been recently developed in Italy, in the
frame of an international scientific collaboration. This aircraft can be operated to measure fluxes of mass, momentum
and energy while flying at low altitude and reduced ground speed. The fluxes are computed with the
airborne eddy correlation technique. The basic theory at the basis of the flux measurement technique is also described
in the paper, and two application examples are discussed to illustrate the quality and the accuracy of the
measurements that can be made using this research platform. Potential applications of those data to parametrize
land surface schemes, validate simulation models and provide extensive and reliable ground truthing for satellite
remote sensing applications are highlighted
Investigation of genomic DNA methylation by ultraviolet resonant Raman spectroscopy
Cytosine plays a preeminent role in DNA methylation, an epigenetic mechanism that regulates gene expression, the misregulation of which can lead to severe diseases. Several methods are nowadays employed for assessing the global DNA methylation levels, but none of them combines simplicity, high sensitivity, and low operating costs to be translated into clinical applications. Ultraviolet (UV) resonant Raman measurements at excitation wavelengths of 272 nm, 260 nm, 250 nm, and 228 nm have been carried out on isolated deoxynucleoside triphosphates (dNTPs), on a dNTP mixture as well as on genomic DNA (gDNA) samples, commercial from salmon sperm and non-commercial from B16 murine melanoma cell line. The 228 nm excitation wavelength was identified as the most suitable energy for enhancing cytosine signals over the other DNA bases. The UV Raman measurements performed at this excitation wavelength on hyper-methylated and hypo-methylated DNA from Jurkat leukemic T-cell line have revealed significant spectral differences with respect to gDNA isolated from salmon sperm and mouse melanoma B16 cells. This demonstrates how the proper choice of the excitation wavelength, combined with optimized extraction protocols, makes UV Raman spectroscopy a suitable technique for highlighting the chemical modifications undergone by cytosine nucleotides in gDNA upon hyper- and hypo-methylation events
Optically variable active galactic nuclei in the 3 yr VST survey of the COSMOS field
The analysis of the variability of active galactic nuclei (AGNs) at different
wavelengths and the study of possible correlations among different spectral
windows are nowadays a major field of inquiry. Optical variability has been
largely used to identify AGNs in multivisit surveys. The strength of a
selection based on optical variability lies in the chance to analyze data from
surveys of large sky areas by ground-based telescopes. However the
effectiveness of optical variability selection, with respect to other
multiwavelength techniques, has been poorly studied down to the depth expected
from next generation surveys. Here we present the results of our r-band
analysis of a sample of 299 optically variable AGN candidates in the VST survey
of the COSMOS field, counting 54 visits spread over three observing seasons
spanning > 3 yr. This dataset is > 3 times larger in size than the one
presented in our previous analysis (De Cicco et al. 2015), and the observing
baseline is ~8 times longer. We push towards deeper magnitudes (r(AB) ~23.5
mag) compared to past studies; we make wide use of ancillary multiwavelength
catalogs in order to confirm the nature of our AGN candidates, and constrain
the accuracy of the method based on spectroscopic and photometric diagnostics.
We also perform tests aimed at assessing the relevance of dense sampling in
view of future wide-field surveys. We demonstrate that the method allows the
selection of high-purity (> 86%) samples. We take advantage of the longer
observing baseline to achieve great improvement in the completeness of our
sample with respect to X-ray and spectroscopically confirmed samples of AGNs
(59%, vs. ~15% in our previous work), as well as in the completeness of
unobscured and obscured AGNs. The effectiveness of the method confirms the
importance to develop future, more refined techniques for the automated
analysis of larger datasets.Comment: 21 pages, 10 figures; accepted for publication in A&
The Expanding Universe of Prion Diseases
Prions cause fatal and transmissible neurodegenerative disease. These etiological infectious agents are formed in greater part from a misfolded cell-surface protein called PrP(C). Several mammalian species are affected by the diseases, and in the case of “mad cow disease” (BSE) the agent has a tropism for humans, with negative consequences for agribusiness and public health. Unfortunately, the known universe of prion diseases is expanding. At least four novel prion diseases—including human diseases variant Creutzfeldt-Jakob disease (vCJD) and sporadic fatal insomnia (sFI), bovine amyloidotic spongiform encephalopathy (BASE), and Nor98 of sheep—have been identified in the last ten years, and chronic wasting disease (CWD) of North American deer (Odocoileus Specis) and Rocky Mountain elk (Cervus elaphus nelsoni) is undergoing a dramatic spread across North America. While amplification (BSE) and dissemination (CWD, commercial sourcing of cervids from the wild and movement of farmed elk) can be attributed to human activity, the origins of emergent prion diseases cannot always be laid at the door of humankind. Instead, the continued appearance of new outbreaks in the form of “sporadic” disease may be an inevitable outcome in a situation where the replicating pathogen is host-encoded
SUDARE-VOICE variability-selection of Active Galaxies in the Chandra Deep Field South and the SERVS/SWIRE region
One of the most peculiar characteristics of Active Galactic Nuclei (AGN) is
their variability over all wavelengths. This property has been used in the past
to select AGN samples and is foreseen to be one of the detection techniques
applied in future multi-epoch surveys, complementing photometric and
spectroscopic methods.
In this paper, we aim to construct and characterise an AGN sample using a
multi-epoch dataset in the r band from the SUDARE-VOICE survey.
Our work makes use of the VST monitoring program of an area surrounding the
Chandra Deep Field South to select variable sources. We use data spanning a six
month period over an area of 2 square degrees, to identify AGN based on their
photometric variability.
The selected sample includes 175 AGN candidates with magnitude r < 23 mag. We
distinguish different classes of variable sources through their lightcurves, as
well as X-ray, spectroscopic, SED, optical and IR information overlapping with
our survey.
We find that 12% of the sample (21/175) is represented by SN. Of the
remaining sources, 4% (6/154) are stars, while 66% (102/154) are likely AGNs
based on the available diagnostics. We estimate an upper limit to the
contamination of the variability selected AGN sample of about 34%, but we point
out that restricting the analysis to the sources with available
multi-wavelength ancillary information, the purity of our sample is close to
80% (102 AGN out of 128 non-SN sources with multi-wavelength diagnostics). Our
work thus confirms the efficiency of the variability selection method in
agreement with our previous work on the COSMOS field; in addition we show that
the variability approach is roughly consistent with the infrared selection.Comment: Published in A & A, 15 pages, 6 figure
Supernova rates from the SUDARE VST-Omegacam search II. Rates in a galaxy sample
This is the second paper of a series in which we present measurements of the
Supernova (SN) rates from the SUDARE survey. In this paper, we study the trend
of the SN rates with the intrinsic colours, the star formation activity and the
mass of the parent galaxies. We have considered a sample of about 130000
galaxies and a SN sample of about 50 events. We found that the SN Ia rate per
unit mass is higher by a factor of six in the star-forming galaxies with
respect to the passive galaxies. The SN Ia rate per unit mass is also higher in
the less massive galaxies that are also younger. These results suggest a
distribution of the delay times (DTD) less populated at long delay times than
at short delays. The CC SN rate per unit mass is proportional to both the sSFR
and the galaxy mass. The trends of the Type Ia and CC SN rates as a function of
the sSFR and the galaxy mass that we observed from SUDARE data are in agreement
with literature results at different redshifts. The expected number of SNe Ia
is in agreement with the observed one for all four DTD models considered both
in passive and star-forming galaxies so we can not discriminate between
different progenitor scenarios. The expected number of CC SNe is higher than
the observed one, suggesting a higher limit for the minimum progenitor mass. We
also compare the expected and observed trends of the SN Ia rate with the
intrinsic U - J colour of the parent galaxy, assumed as a tracer of the age
distribution. While the slope of the relation between the SN Ia rate and the U
- J color in star-forming galaxies can be reproduced well by all four DTD
models considered, only the steepest of them is able to account for the rates
and colour in star-forming and passive galaxies with the same value of the SN
Ia production efficiency.Comment: A& A accepte
"Your Skin Tells You" Campaign for Keratinocyte Cancers: When Individuals' Selection Makes the Difference
Background: Prevention campaigns for skin cancers have focused primarily on melanoma, and over time there has been increasing awareness of the need to select the population to be screened to maximize program effectiveness. Objectives: The objective of the study was to report the results of a free dermatological initiative, as part of an awareness campaign dedicated to keratinocyte cancers, targeting individuals pre-selected through a short questionnaire. Methods: One day of dermatological consultations was held at 15 dermato-oncology referral centers during May 22-June 30, 2021. For selection, individuals answered a telephone interview consisting of 7 yes/no questions on risk factors. Demographics, clinical characteristics of suspicious tumors, and histopathologic diagnosis of excised lesions were collected. Suspicion rate, detection rate, and positive predictive values (PPVs) for any skin cancer, basal cell carcinoma (BCC), cutaneous squamous cell carcinoma (cSCC), and melanoma were calculated. Results: A total of 320 individuals (56.9% males; 43.1% females) with a median age of 69.6 (range 21-91) years qualified for the screening initiative. Overall, skin cancers and precancerous lesions were diagnosed in 65.9% of the patients. Suspicion rate was 28.7% for any skin cancer (92/320), 22.8% for BCC (73/320), 4.7% for cSCC (15/320), and 1.2% for melanoma (4/320). Detection rate was 23.4% for any skin cancer (PPV 93.7%), 18.1% for BCC (PPV 95.1%), 4.4% for cSCC (PPV 93.3%), and 0.9% for melanoma (PPV 75%). Conclusions: Selection of individuals at high risk is a cost-effective approach for early detection campaigns for keratinocyte cancers
Standard and Light-Cycler PCR methods for animal DNA species detection in animal feedstuffs
In this work four species-specific primers and probes were designed and evaluated for the detection and quantification of bovine, ovine, swine and chicken mitochondrial DNA in feeds. PCR primers were optimized using conventional and Real Time PCR, to detect short species-specific sequences amplifiable from heat treated material. Both methods confirmed the high specificity of the primers designed. Real time quantitative PCR assay allowed the detection of as few as 0.01 ng and 0.05 ng of ovine and bovine genomic DNA, respectively. The detection limit for swine and chicken genomic DNA was 0.5 ng. Sensitivity levels observed in DNA extracted from meat samples processed according to EU legislation were different compared to those in genomic DNAs previously described. They resulted in swine 5 fg of MBM DNA, in chicken 25 ng, in ovine and bovine 50 ng. We confirmed the efficiency and specificity of primers in RT-PCR to detect 0.5% of bovine, ovine, swine and chicken MBM in contaminated feedstuffs. (C) 2007 Elsevier Ltd. All rights reserved
A Survey of Volunteered Open Geo-Knowledge Bases in the Semantic Web
Over the past decade, rapid advances in web technologies, coupled with
innovative models of spatial data collection and consumption, have generated a
robust growth in geo-referenced information, resulting in spatial information
overload. Increasing 'geographic intelligence' in traditional text-based
information retrieval has become a prominent approach to respond to this issue
and to fulfill users' spatial information needs. Numerous efforts in the
Semantic Geospatial Web, Volunteered Geographic Information (VGI), and the
Linking Open Data initiative have converged in a constellation of open
knowledge bases, freely available online. In this article, we survey these open
knowledge bases, focusing on their geospatial dimension. Particular attention
is devoted to the crucial issue of the quality of geo-knowledge bases, as well
as of crowdsourced data. A new knowledge base, the OpenStreetMap Semantic
Network, is outlined as our contribution to this area. Research directions in
information integration and Geographic Information Retrieval (GIR) are then
reviewed, with a critical discussion of their current limitations and future
prospects
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